Computer tomography of liver in alveolar echinococcosis treated with albendazole

Trans R Soc Trop Med Hyg. 1993 May-Jun;87(3):319-21. doi: 10.1016/0035-9203(93)90147-i.

Abstract

Fourteen cases of alveolar echinococcosis were examined by computed tomographic (CT) scanning of the liver, including 3 cases before treatment and 11 cases 2.0-7.5 years after long-term continuous albendazole therapy. In 7 cases the hepatic lesions were almost completely calcified and cured, while in 3 cases incomplete calcification of the peripheral margin of the hepatic lesions was observed. CT scanning of the one uncured case and the 3 cases before treatment showed active lesions with heterogeneous hypodense areas in the liver without calcification on the peripheral margin. Long-term continuous albendazole therapy can result in parasitological cure with death of the parasite.

MeSH terms

  • Adult
  • Albendazole / therapeutic use*
  • Echinococcosis, Hepatic / diagnostic imaging*
  • Echinococcosis, Hepatic / drug therapy
  • Echinococcosis, Hepatic / pathology
  • Female
  • Humans
  • Liver / diagnostic imaging*
  • Liver / pathology
  • Male
  • Middle Aged
  • Time Factors
  • Tomography, X-Ray Computed*
  • Treatment Outcome

Substances

  • Albendazole