Norgestomet and gonadotropin-releasing hormone enhance corpus luteum function and fertility of postpartum suckled beef cows

J Anim Sci. 1993 Oct;71(10):2579-85. doi: 10.2527/1993.71102579x.

Abstract

In Exp. 1,101 suckled beef cows were administered two injections of prostaglandin F2 alpha (PGF2 alpha) 11 d apart. Cows in Group 1 received no additional treatment. Cows in Groups 2 and 3 received 250 micrograms of GnRH plus 47-h calf removal. Cows in Group 3 also received a norgestomet ear implant that was inserted 4 d after the first PGF2 alpha injection and left in situ for 8 d. The second PGF2 alpha injection was administered approximately 28 h before the time of norgestomet implant removal. The GnRH was administered approximately 30 h after the time of norgestomet implant removal (or 58 h after the second PGF2 alpha injection). Calf removal was the period from the time of implant removal to AI. All cows were artificially inseminated once 75 h after the second PGF2 alpha injection (47 h after implant removal). Reproductive status before the time of GnRH treatment (presynchronization) was determined by multiple sampling (2, 13, and 23 d before GnRH treatment) for blood progesterone concentrations (62% anestrous and 38% cyclic). The GnRH treatment increased (P < .01) the ovulation response and norgestomet reduced (P < .01) the incidence of short luteal phases in the presynchronization anestrous cows. Norgestomet treatment increased (P < .05) the timed breeding pregnancy rates for both presynchronization anestrous and cyclic cows. In Exp. 2, 174 suckled beef cows were administered Syncro-Mate B (which includes norgestomet). Cows in Group 1 received no additional treatment, whereas cows in Group 2 received 250 micrograms of GnRH (30 h after norgestomet implant removal).(ABSTRACT TRUNCATED AT 250 WORDS)

MeSH terms

  • Anestrus / drug effects
  • Anestrus / physiology
  • Animals
  • Capsules
  • Cattle / physiology*
  • Corpus Luteum / drug effects*
  • Corpus Luteum / physiology
  • Dinoprost / pharmacology
  • Drug Implants
  • Estrus Synchronization
  • Female
  • Fertility / drug effects*
  • Gonadotropin-Releasing Hormone / administration & dosage
  • Gonadotropin-Releasing Hormone / pharmacology*
  • Injections, Intramuscular / veterinary
  • Insemination, Artificial / veterinary
  • Ovulation / drug effects
  • Postpartum Period / drug effects
  • Postpartum Period / physiology
  • Pregnancy
  • Pregnenediones / administration & dosage
  • Pregnenediones / pharmacology*
  • Progesterone Congeners / administration & dosage
  • Progesterone Congeners / pharmacology
  • Random Allocation

Substances

  • Capsules
  • Drug Implants
  • Pregnenediones
  • Progesterone Congeners
  • Gonadotropin-Releasing Hormone
  • norgestomet
  • Dinoprost