Mapping of ben genes of Pseudomonas aeruginosa

FEMS Microbiol Lett. 1993 Sep 15;112(3):255-9. doi: 10.1016/0378-1097(93)90609-6.

Abstract

Four ben genes responsible for the conversion of benzoate to catechol in Pseudomonas aeruginosa PAO have been mapped to a 4.6 kb KpnI fragment, ben-1 and ben-4 were known to be separate genes but now ben-1508 has been found to be different from ben-2. The two genes were distinguished by Tn5 mutagenesis of a cosmid clone and deletion mapping. It is likely that the four genes mapped (ben-4, ben-2, ben-1508 and ben-1) correspond to the previously characterized benR (regulatory gene) and benABC (benzoate dioxygenase) respectively.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzoates / metabolism*
  • Catechols / metabolism*
  • Chromosome Mapping*
  • Genes, Bacterial*
  • Mutagenesis, Insertional
  • Pseudomonas aeruginosa / genetics*
  • Restriction Mapping
  • Sequence Deletion

Substances

  • Benzoates
  • Catechols
  • catechol