Human alpha 1-antichymotrypsin of pancreatic origin carries blood group determinants

Biol Chem Hoppe Seyler. 1993 Jul;374(7):455-9. doi: 10.1515/bchm3.1993.374.7-12.455.

Abstract

alpha 1-Antichymotrypsin was detected as a minor but normal component of pancreatic juice and found, with the aid of monoclonal antibodies and lectins, to differ from serum alpha 1-antichymotrypsin with respect to its carbohydrate moiety. alpha 1-Antichymotrypsin carries blood group determinants, as is typical for glycoproteins of pancreatic origin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Monoclonal / immunology
  • Blood Group Antigens / immunology*
  • Carbohydrates / analysis
  • Digoxigenin
  • Electrophoresis, Polyacrylamide Gel
  • Humans
  • Immunoenzyme Techniques
  • Lectins
  • Pancreas / chemistry
  • Pancreas / immunology*
  • Pancreatic Juice / chemistry
  • Polysaccharides / analysis
  • alpha 1-Antichymotrypsin / blood
  • alpha 1-Antichymotrypsin / immunology*
  • alpha 1-Antichymotrypsin / isolation & purification

Substances

  • Antibodies, Monoclonal
  • Blood Group Antigens
  • Carbohydrates
  • Lectins
  • Polysaccharides
  • alpha 1-Antichymotrypsin
  • Digoxigenin