Piecewise exponential survival curves with smooth transitions

Math Biosci. 1994 Apr;120(2):233-50. doi: 10.1016/0025-5564(94)90054-x.

Abstract

Several models of a population survival curve composed of two piecewise exponential distributions are developed. In one formulation the hazard rate changes at a point that is an unobservable random variable that varies between individuals. The population hazard function may decrease with age even when all individuals' hazards are increasing. In a second formulation, the population hazard function is modeled directly. Several models are fit to the survival history of a cohort of 5751 highly inbred male Drosophila melanogaster and the British coal mining disaster data.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Coal Mining
  • Drosophila melanogaster
  • Humans
  • Male
  • Mathematics
  • Models, Biological
  • Proportional Hazards Models
  • Survival Analysis*
  • United Kingdom