Granulocytic sarcoma showing chromosomal changes other than the t(8;21)

Cancer Genet Cytogenet. 1994 May;74(1):59-61. doi: 10.1016/0165-4608(94)90030-2.

Abstract

Cytogenetic analysis of a granulocytic sarcoma showed a 46,XX,der(X)t(X;1) (q28;q22), inv(3)(p21q27), inv(9)(p13q22),t(12;22)(p11;q11) karyotype. In addition, bone marrow aspirate disclosed the presence of cells with a 46,XX,inv(3)(p21q27),inv(9)(p13q22)(p11;q11) chromosomal pattern while the patient was clinically aleukemic. This case demonstrates that chromosomal abnormalities other than the classical t(8;21) can also be associated with granulocytic sarcoma.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosome Aberrations*
  • Chromosomes, Human, Pair 21
  • Chromosomes, Human, Pair 8
  • Female
  • Humans
  • Infant
  • Karyotyping
  • Leukemia, Myeloid / genetics*
  • Lymph Nodes / ultrastructure
  • Translocation, Genetic