Cross correlations between 4 homologous pairs of ear-reference derivations were calculated for 45-sec digitized samples of typical active and quiet sleep in 19 selected normal newborns at 21--70 h after term birth. Repeat recordings were obtained in 9 subjects 24 h after the original recordings and another set of cross correlations was calculated. For comparison, similar recordings were obtained from 4 asymptomatic young adults and cross correlations were calculated for 45-sec samples of typical stage 4 and stage REM sleep and for stage W both before and after sleep. Mean cross-correlation coefficients at zero time lag were generally higher for the adult sleep data than for the newborn data, but the differences were smaller than had been anticipated. The coefficients for active sleep data in the newborns were higher than for quiet sleep data, while in the adults the coefficients were higher for stage 4 than for stage REM. Coefficients were higher for convexity derivations than for temporal derivations in both newborns and adults. A review of the small available literature suggests that recording and analysis techniques may be significant variables determining the results obtained in such studies. The cross-correlation method of measuring interhemispheric synchrony may prove useful in identifying brain disorders in the postnatal period.