[Skin lesions as a rare initial symptom of Kahler's disease]

Ned Tijdschr Geneeskd. 1994 Mar 5;138(10):526-8.
[Article in Dutch]

Abstract

Multiple skin lesions developed in a 70 year-old-man. Pathological examination revealed plasmacytomas. Because of the presence of a IgD paraprotein and 15% abnormal plasma cells in the bone marrow Kahler's disease of the IgD type was diagnosed. In accordance with literature the course of the disease was rapidly progressive. After an initial favourable response to chemotherapy and radiotherapy, the patient died one year after diagnosis. Extraosseous tissue involvement and hepatosplenomegaly are well-known phenomenon of IgD-Kahler's disease. Skin plasmacytomas as the first symptom of the disease are very rare.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Combined Modality Therapy
  • Drug Therapy, Combination
  • Humans
  • Male
  • Melphalan / administration & dosage
  • Multiple Myeloma / diagnosis*
  • Multiple Myeloma / pathology
  • Multiple Myeloma / therapy
  • Prednisone / administration & dosage
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / pathology
  • Skin Neoplasms / therapy

Substances

  • Melphalan
  • Prednisone