Regulation of coumarin 7-hydroxylation in man

J Cancer Res Clin Oncol. 1994:120 Suppl:S30-1. doi: 10.1007/BF01377121.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Aryl Hydrocarbon Hydroxylases*
  • Coumarins / pharmacokinetics*
  • Cytochrome P-450 CYP2A6
  • Cytochrome P-450 Enzyme System / metabolism
  • Humans
  • Hydroxylation
  • Liver / enzymology
  • Liver / metabolism*
  • Liver Diseases / metabolism
  • Mice
  • Mixed Function Oxygenases / metabolism
  • Prodrugs / pharmacokinetics*
  • Umbelliferones / metabolism*
  • Umbelliferones / urine

Substances

  • Coumarins
  • Prodrugs
  • Umbelliferones
  • 7-hydroxycoumarin
  • Cytochrome P-450 Enzyme System
  • coumarin
  • Mixed Function Oxygenases
  • Aryl Hydrocarbon Hydroxylases
  • Cytochrome P-450 CYP2A6