A multisubunit complex containing the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated from yeast

Proc Natl Acad Sci U S A. 1994 Mar 1;91(5):1950-4. doi: 10.1073/pnas.91.5.1950.

Abstract

A complex containing the products of the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 genes and four additional polypeptides has been purified from extracts of the yeast Saccharomyces cerevisiae. Physical association of these proteins was demonstrated by copurification and coimmunoprecipitation. A potent DNA-dependent ATPase copurified with the complex, and this activity was evidently associated with SWI2/SNF2.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adenosine Triphosphatases / genetics
  • Adenosine Triphosphatases / isolation & purification
  • Base Sequence
  • Chromosomal Proteins, Non-Histone
  • DNA Helicases*
  • DNA Primers / genetics
  • DNA, Fungal / genetics
  • DNA-Binding Proteins / genetics
  • DNA-Binding Proteins / isolation & purification
  • Fungal Proteins / genetics*
  • Fungal Proteins / isolation & purification*
  • Genes, Fungal
  • Macromolecular Substances
  • Molecular Sequence Data
  • Nuclear Proteins*
  • SMARCB1 Protein
  • Saccharomyces cerevisiae / genetics*
  • Saccharomyces cerevisiae Proteins
  • Transcription Factors / genetics
  • Transcription Factors / isolation & purification
  • Transcription, Genetic

Substances

  • Chromosomal Proteins, Non-Histone
  • DNA Primers
  • DNA, Fungal
  • DNA-Binding Proteins
  • Fungal Proteins
  • Macromolecular Substances
  • Nuclear Proteins
  • SMARCB1 Protein
  • SMARCB1 protein, human
  • SNF5 protein, S cerevisiae
  • Saccharomyces cerevisiae Proteins
  • Transcription Factors
  • Adenosine Triphosphatases
  • SNF2 protein, S cerevisiae
  • DNA Helicases