Three CA/GT repeat polymorphisms from loci D21S414 and D21S1234 on human chromosome 21

Hum Genet. 1994 Mar;93(3):359-60. doi: 10.1007/BF00212043.

Abstract

We report three new polymorphic CA repeat microsatellites (ABM-21, ABM-C37A, and ABM-C37B) in two different loci (D21S414 and D21S1234), located in bands q21 and q11.2 of human chromosome 21 (HC21) and that were isolated from a HC21 phage library (LA21NS01). Heterozygosities for ABM-21, ABM-C37A, and ABM-C37B were 0.74, 0.50, and 0.67 respectively. These three CA repeat markers should be useful in the construction of a high resolution genetic map of this region of HC21.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Base Sequence
  • Chromosome Mapping
  • Chromosomes, Human, Pair 21*
  • DNA Primers
  • DNA, Satellite
  • Female
  • Gene Frequency
  • Genetic Markers
  • Heterozygote
  • Humans
  • Male
  • Molecular Sequence Data
  • Pedigree
  • Polymerase Chain Reaction
  • Polymorphism, Genetic*
  • Repetitive Sequences, Nucleic Acid*

Substances

  • DNA Primers
  • DNA, Satellite
  • Genetic Markers

Associated data

  • GENBANK/Z22789
  • GENBANK/Z22793
  • GENBANK/Z25523