Atlantic cod cDNA encoding a psychrophilic chymotrypsinogen

Biochim Biophys Acta. 1994 Sep 13;1219(1):211-4. doi: 10.1016/0167-4781(94)90274-7.

Abstract

A cDNA clone encoding a psychrophilic cod chymotrypsinogen has been isolated and characterized. The predicted amino acid sequence reveals a preproenzyme of 263 amino acids containing a unique 18 residue signal sequence. Amino acid sequence identity between the cod and mammalian chymotrypsinogens is 64-68%. Two highly conserved proline residues are substituted in cod chymotrypsin.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Atlantic Ocean
  • Base Sequence
  • Chymotrypsinogen / classification
  • Chymotrypsinogen / genetics*
  • Cloning, Molecular
  • Cold Temperature
  • DNA, Complementary / genetics
  • Enzyme Precursors / genetics*
  • Fishes / genetics*
  • Marine Biology
  • Molecular Sequence Data
  • Sequence Analysis, DNA
  • Sequence Homology, Amino Acid

Substances

  • DNA, Complementary
  • Enzyme Precursors
  • prechymotrypsinogen 2
  • Chymotrypsinogen

Associated data

  • GENBANK/X78490