Abstract
The rifampin-resistance mutation of LS3,an asporogenous mutant of Bacillus subtilis 3610, leads to altered mobility of the beta subunit of ribonucleic acid polymerase in sodium dodecyl sulfate-polyacrylamide slab gel electrophoresis. This finding argues that the rifampin-resistance mutation is located in the structural gene coding for the beta polypeptide.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Bacillus subtilis / drug effects
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Bacillus subtilis / enzymology*
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Bacillus subtilis / growth & development
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DNA-Directed RNA Polymerases* / analysis
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Drug Resistance, Microbial*
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Electrophoresis, Polyacrylamide Gel
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Genes
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Mutation*
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Peptides / analysis
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Phenotype
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Rifampin / pharmacology*
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Spores, Bacterial / growth & development
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Transformation, Genetic
Substances
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Peptides
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DNA-Directed RNA Polymerases
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Rifampin