Adductor laryngeal breathing dystonia in a patient with lubag (X-linked dystonia-Parkinsonism syndrome)

Mov Disord. 1994 May;9(3):318-20. doi: 10.1002/mds.870090307.

Abstract

We report a patient with Lubag (X-linked dystonia-parkinsonism) who presented with severe respiratory stridor from adductor laryngeal breathing dystonia. Emergency tracheostomy was necessary, and subsequent laryngeal injection with botulinum toxin led to worsening aspiration. Botulinum toxin injection for severe lingual dystonia was successful.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Airway Obstruction / diagnosis
  • Airway Obstruction / drug therapy
  • Airway Obstruction / genetics*
  • Antiparkinson Agents / adverse effects
  • Antiparkinson Agents / therapeutic use
  • Botulinum Toxins / adverse effects
  • Botulinum Toxins / therapeutic use
  • Carbidopa / adverse effects
  • Carbidopa / therapeutic use
  • Dose-Response Relationship, Drug
  • Drug Therapy, Combination
  • Dystonia / diagnosis
  • Dystonia / drug therapy
  • Dystonia / genetics*
  • Electromyography / drug effects
  • Genes, Recessive / genetics*
  • Humans
  • Injections, Intramuscular
  • Laryngeal Diseases / diagnosis
  • Laryngeal Diseases / drug therapy
  • Laryngeal Diseases / genetics*
  • Levodopa / adverse effects
  • Levodopa / therapeutic use
  • Male
  • Middle Aged
  • Parkinson Disease / diagnosis
  • Parkinson Disease / drug therapy
  • Parkinson Disease / genetics*
  • Respiration Disorders / diagnosis
  • Respiration Disorders / drug therapy
  • Respiration Disorders / genetics*
  • Respiratory Insufficiency / diagnosis
  • Respiratory Insufficiency / drug therapy
  • Respiratory Insufficiency / genetics*
  • Respiratory Sounds / diagnosis
  • Respiratory Sounds / genetics
  • Sex Chromosome Aberrations / genetics*
  • X Chromosome*

Substances

  • Antiparkinson Agents
  • Levodopa
  • Botulinum Toxins
  • Carbidopa