Calcitonin-secreting ovarian strumal carcinoid

Eur J Gynaecol Oncol. 1994;15(3):211-6.

Abstract

A 3-mm strumal carcinoid was found incidentally in a mature ovarian cystic teratoma of a 38-year-old woman followed up for more than 9 years. Although the thyroid component disclosed a typical normal light microscopic appearance, no thyroglobulin and thyroxine were detected immunohistochemically. Immunoreactive calcitonin was demonstrated within the tumour cells. The close relationship between functionally imperfect thyroid tissue and a neuroendocrine marker-secreting tumour seems to be concordant with the theory of the existence of a pluripotential stem cell capable of differentiating multidirectionally.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Calcitonin / metabolism*
  • Carcinoid Tumor / metabolism*
  • Carcinoid Tumor / pathology
  • Cell Nucleus / ultrastructure
  • Cytoplasm / ultrastructure
  • Female
  • Follow-Up Studies
  • Humans
  • Neoplasms, Multiple Primary / pathology*
  • Ovarian Neoplasms / metabolism*
  • Ovarian Neoplasms / pathology
  • Struma Ovarii / metabolism*
  • Struma Ovarii / pathology
  • Teratoma / pathology*
  • Thyroid Gland / pathology

Substances

  • Calcitonin