Mandibular arteriovenous malformation (AVM) is a potentially life-threatening pathology requiring radical treatment. We report two female patients, aged 14 and 16 years, in whom occlusion of the AVM with Ethibloc after percutaneous transosseous puncture achieved definitive recovery. The first case was treated by direct injection of Ethibloc following inefficient arterial embolization with Ivalon particles. In the second case, Ethibloc was injected without previous arterial embolization. Control examinations performed at 6 months and 2 years confirmed complete calcification of the mandible in the first case and a total obliteration of the AVM on angiography in the second case.