N-glycosylated protein(s) are important for the infectivity of Borna disease virus (BDV)

R Stoyloff; T Briese; K Borchers; W Zimmermann; H Ludwig

doi:10.1007/BF01309486

N-glycosylated protein(s) are important for the infectivity of Borna disease virus (BDV)

Arch Virol. 1994;137(3-4):405-9. doi: 10.1007/BF01309486.

Authors

R Stoyloff¹, T Briese, K Borchers, W Zimmermann, H Ludwig

Affiliation

¹ Institut für Virologie, Freie Universität Berlin, Federal Republic of Germany.

PMID: 7944960
DOI: 10.1007/BF01309486

Abstract

Tunicamycin inhibited the production of infectious Borna disease virus (BDV) and glycosidase treatment eliminated the infectivity of cell-free virus. A glycoprotein of approximately 17 kDa, found in association with infectious virus, was identified by Concanavalin A binding.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Borna disease virus / drug effects
Borna disease virus / pathogenicity*
Cell Line
Glycoside Hydrolases
Glycosylation / drug effects
Humans
Oligodendroglia / virology
Tunicamycin / pharmacology
Viral Envelope Proteins / drug effects
Viral Envelope Proteins / metabolism
Viral Envelope Proteins / physiology*

Substances

Viral Envelope Proteins
Tunicamycin
Glycoside Hydrolases