Preliminary results of Pneumocystis carinii strain differentiation by using molecular biology

J Clin Microbiol. 1994 Dec;32(12):3052-3. doi: 10.1128/jcm.32.12.3052-3053.1994.

Abstract

The mode of Pneumocystis carinii transmission is controversial. Recent studies point to exogenous inoculation rather than reactivation, and person-to-person transmission has also been suggested. Comparison of nucleotide sequences of the large-subunit mitochondrial rRNA gene of P. carinii from human immunodeficiency virus-seropositive patients showed strain differences.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • AIDS-Related Opportunistic Infections / microbiology*
  • Base Sequence
  • DNA, Fungal / analysis
  • Genetic Variation
  • HIV Seropositivity
  • Humans
  • Molecular Sequence Data
  • Pneumocystis / genetics*
  • Pneumocystis / isolation & purification
  • Pneumonia, Pneumocystis / microbiology*
  • Polymerase Chain Reaction
  • RNA, Fungal / genetics
  • RNA, Ribosomal / genetics

Substances

  • DNA, Fungal
  • RNA, Fungal
  • RNA, Ribosomal

Associated data

  • GENBANK/S77852