Identification of a single base polymorphism in intron 2 of the c-fos gene and its detection by mismatched PCR-RFLP

Jpn J Hum Genet. 1994 Dec;39(4):439-40. doi: 10.1007/BF01892390.

Abstract

A T-->C transition in intron 2 of the c-fos gene was identified by sequencing analysis (Fig. 1). A simple method to detect this polymorphism was developed by mismatched PCR-RFLP. Allele frequency of this polymorphism was determined in the Japanese and in the Caucasian, separately.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Genes, fos / genetics*
  • Humans
  • Introns / genetics*
  • Japan
  • Molecular Sequence Data
  • Polymerase Chain Reaction / methods*
  • Polymorphism, Restriction Fragment Length*
  • White People