Intermediate lymphocytic lymphoma with both t(14;19)(q32.3;q13.1) and t(3;22)(q27;q11.2)

M Nakagawa; H Sugiyama; H Ogawa; S Tone; H Morishita; H Ikeda; K Aozasa; M Taniwaki; T Abe; T Kishimoto

doi:10.1016/0165-4608(94)00094-r

Intermediate lymphocytic lymphoma with both t(14;19)(q32.3;q13.1) and t(3;22)(q27;q11.2)

Cancer Genet Cytogenet. 1995 Jan;79(1):89-91. doi: 10.1016/0165-4608(94)00094-r.

Authors

M Nakagawa¹, H Sugiyama, H Ogawa, S Tone, H Morishita, H Ikeda, K Aozasa, M Taniwaki, T Abe, T Kishimoto

Affiliation

¹ Osaka University medical School, Department of Medicine III, Japan.

PMID: 7850761
DOI: 10.1016/0165-4608(94)00094-r

Abstract

Chromosome translocations involving various chromosomes sites, including the sites of immunoglobulin loci (14q32,2p12,22q11) represent recurrent aberration in non-Hodgkin lymphoma (NHL). We report a novel case of intermediate lymphocytic lymphoma (ILL) with both t(14;19)(q32.3;q13.1) and t(3;22)(q27;q11.2). The t(14;19)(q32.3;q13.1) and t(3;22) (q27;q11.2) may represent reciprocal recombinations between immunoglobulin (Ig) H chain gene (14q32.3) and bcl-3(19q13.1) and between Ig lambda chain gene (22q11.2) and bcl-6 (3q27), respectively.

Publication types

Case Reports

MeSH terms

Aged
Chromosomes, Human, Pair 14*
Chromosomes, Human, Pair 19*
Chromosomes, Human, Pair 22*
Chromosomes, Human, Pair 3*
Humans
Karyotyping
Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
Male
Translocation, Genetic*