Background: The major problem of eosinophilic pustular folliculitis (EPF) is its generally unknown aetiology.
Objective and methods: The purpose of this case report is to advise a thorough medical investigation of all patients with EPF.
Results: The case of EPF presented seems to be associated with a chronic B-cell lymphatic leukaemia.
Conclusion: Before regarding EPF as an idiopathic disease of unknown aetiology a thorough immunologic and haematologic investigation has to be advocated.