Abstract
Two patients with eosinophilic endomyocardial disease related to peripheral T-cell lymphomas are reported. Both patients were free of cardiac symptoms at presentation and during follow-up. Routine two dimensional echocardiography revealed bi-apical ventricular obliteration, which was also seen on MR imaging. On the T1-weighted sequence, the thickened endocardium appeared with an isointense signal. Gadolinium DOTA provided an enhanced contrast of the internal part of the left ventricular wall. On T2-weighted sequence, a thin hypointense curvilinear structure drew a dividing line between the internal, endocardial, and the external, myocardial area. Left-ventricular systolic and diastolic functions remained unaltered during subsequent follow-up.
MeSH terms
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Adult
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Cardiomyopathies / diagnosis
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Cardiomyopathies / etiology*
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Contrast Media
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Doxorubicin / administration & dosage
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Echocardiography
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Echocardiography, Doppler, Pulsed
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Endocardium / pathology
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Epirubicin / administration & dosage
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Heterocyclic Compounds
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Humans
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Hypereosinophilic Syndrome / diagnosis
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Hypereosinophilic Syndrome / etiology*
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Lymphoma, T-Cell, Peripheral / complications*
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Lymphoma, T-Cell, Peripheral / drug therapy
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Magnetic Resonance Imaging
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Male
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Myocardium / pathology
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Organometallic Compounds
Substances
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Contrast Media
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Heterocyclic Compounds
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Organometallic Compounds
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Epirubicin
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Doxorubicin
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gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate