Postoperative bone re-growth in lumbar spinal stenosis. A multivariate analysis of 48 patients

Spine (Phila Pa 1976). 1994 Oct 1;19(19):2144-9. doi: 10.1097/00007632-199410000-00003.

Abstract

Study design: Forty-eight patients who underwent posterior decompressive surgery for lumbar spinal stenosis were studied. The effect of bone re-growth after posterior decompression in lumbar spinal stenosis on clinical outcome and the factors promoting the bone re-growth were investigated with a multivariate analysis model.

Methods: Bone re-growth at the sites operated upon was evaluated as a percentage of re-growth of the original laminectomy site based upon plain radiographs. The degree of bone re-growth was classified into four groups: 1) no significant re-growth (Group I, bone regrowth rate 10% or less); mild (Group II, 11% to 40%), moderate (Group III, 41% to 70%), and marked (Group IV, 71% to 100%). The average follow-up period was 4.5 years (range, 2 to 7 years).

Results: No significant bone re-growth was shown in 6% of the patients. Mild re-growth was shown in 50%, moderate re-growth in 29%, and marked re-growth in 15%. A multivariate analysis indicated that a total block in the preoperative myelogram, a follow-up period of more than 5 years, decompression at more than three spinal levels, and age under 60 years were associated with moderate or marked bone re-growth. Spinal instability accelerated the bone re-growth mainly in the mid and later follow-up intervals. Spinal levels adjacent to a fusion showed more bone re-growth. Patients with moderate and marked bone re-growth had poorer clinical outcomes than those with no significant and mild bone re-growth.

Conclusion: Bone re-growth in a surgical defect will occur in most patients after posterior decompression. Moderate and marked postoperative bone re-growth are possibly related to recurrence of neurologic symptoms in the middle of and later on in follow-up periods.

MeSH terms

  • Aged
  • Bone Regeneration*
  • Female
  • Follow-Up Studies
  • Humans
  • Laminectomy
  • Lumbar Vertebrae / diagnostic imaging
  • Lumbar Vertebrae / physiopathology*
  • Lumbar Vertebrae / surgery*
  • Male
  • Models, Statistical
  • Multivariate Analysis
  • Postoperative Complications / epidemiology
  • Radiography
  • Spinal Fusion
  • Spinal Stenosis / epidemiology
  • Spinal Stenosis / physiopathology
  • Spinal Stenosis / surgery*
  • Time Factors
  • Treatment Failure