Abstract
TGRLP interactions with the endothelium may increase the likelihood that a suppressed fibrinolytic capacity and/or an increased procoagulant activity enhances the risk for an ischemic event, that is, for the production of a focal thrombus. The cellular mechanisms and characteristics of TGRLP in hyperlipemia and in the postprandial state that contribute to their potential pathology in IHD are considered.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Arteriosclerosis / blood
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Arteriosclerosis / physiopathology*
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Blood Coagulation Factors / physiology*
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Chylomicrons / physiology*
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Endothelium, Vascular / metabolism
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Endothelium, Vascular / physiology
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Fibrinolysis*
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Humans
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Lipoproteins, VLDL / physiology*
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Myocardial Ischemia / blood
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Myocardial Ischemia / physiopathology*
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Receptors, Lipoprotein / physiology
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Thrombosis / complications
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Thrombosis / physiopathology
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Triglycerides / physiology*
Substances
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Blood Coagulation Factors
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Chylomicrons
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Lipoproteins, VLDL
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Receptors, Lipoprotein
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Triglycerides
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very low density lipoprotein triglyceride