Chromosomal localization of a gene, GF1, encoding a novel zinc finger protein reveals a new syntenic region between man and rodents

Cytogenet Cell Genet. 1995;70(3-4):263-7. doi: 10.1159/000134048.

Abstract

The Gfi1 gene encodes a zinc finger protein which binds DNA and is involved in transcriptional regulation. Gfi1 was assigned to the central portion of mouse Chr 5 by interspecific backcross mapping and to human chromosome band 1p22 and rat chromosome band 14p22 by fluorescence in situ hybridization (FISH). Comparative mapping data presented here describes a new syntenic region between man and rodents.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Chromosome Banding
  • Chromosome Mapping*
  • Chromosomes, Human, Pair 1*
  • Cricetinae
  • Crosses, Genetic
  • DNA-Binding Proteins / genetics*
  • Female
  • Hominidae / genetics*
  • Humans
  • Hybrid Cells
  • In Situ Hybridization, Fluorescence
  • Male
  • Mice / genetics*
  • Mice, Inbred C57BL
  • Muridae / genetics
  • Rats / genetics*
  • Transcription Factors*
  • Zinc Fingers / genetics*

Substances

  • DNA-Binding Proteins
  • GFI1 protein, human
  • Gfi1 protein, mouse
  • Gfi1 protein, rat
  • Transcription Factors