[Richter syndrome: morphologic transformation with persistence of the same phenotype]

Sangre (Barc). 1995 Apr;40(2):153-5.
[Article in Spanish]

Abstract

Richter's syndrome is termed as the occurrence of a high-grade lymphoma along with a chronic lymphocytic leukaemia. We report a patient diagnosed as having a CLL evolving into an immunoblastic lymphoma. In spite of this morphologic change, the same identical immunophenotype remained in both types of cells assessed, that is, CLL-type lymphocytes and immunoblastic and lymphoplasmocytoid cells. This event appears to favour the common clonal origin of these two entities.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Humans
  • Immunophenotyping
  • Leukemia, Lymphocytic, Chronic, B-Cell* / immunology
  • Leukemia, Lymphocytic, Chronic, B-Cell* / pathology
  • Lymphoma, Large B-Cell, Diffuse* / immunology
  • Lymphoma, Large B-Cell, Diffuse* / pathology
  • Male
  • Syndrome