Abstract
For many years, viral hepatitis has been considered to be a frequent and serious adverse outcome of blood transfusion. The majority of cases have been due to hepatitis B and C viruses, which, respectively, are DNA and RNA viruses. Both are lipid enveloped and are susceptible to viral inactivation procedures. Careful donor screening and the use tests for HBsAg and anti-HBc have essentially eliminated the risk of transfusion-transmitted HBV infection.
MeSH terms
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Blood Donors
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Hepatitis Antibodies / blood
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Hepatitis B / blood
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Hepatitis B / epidemiology
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Hepatitis B / prevention & control
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Hepatitis B / transmission
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Hepatitis C / blood
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Hepatitis C / epidemiology
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Hepatitis C / prevention & control
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Hepatitis C / transmission
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Hepatitis Viruses / classification
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Hepatitis Viruses / immunology
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Hepatitis Viruses / isolation & purification
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Hepatitis, Viral, Human / blood
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Hepatitis, Viral, Human / epidemiology
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Hepatitis, Viral, Human / prevention & control
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Hepatitis, Viral, Human / transmission*
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Humans
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Mass Screening
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Prevalence
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Seroepidemiologic Studies
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Transfusion Reaction*
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United States / epidemiology
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Viremia / virology