Positron emission tomography and central neurotransmitter systems in movement disorders

Fundam Clin Pharmacol. 1994;8(6):503-17. doi: 10.1111/j.1472-8206.1994.tb00831.x.

Abstract

This article discusses the anatomical and neurochemical structure of the basal ganglia and reviews the Positron Emission Tomographic (PET) ligands available for investigating these pathways. We discuss how clinical PET studies have improved our understanding of the neurochemical changes underlying principal movement disorders.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Basal Ganglia / diagnostic imaging*
  • Dopamine / metabolism
  • Humans
  • Huntington Disease / diagnostic imaging
  • Levodopa / metabolism
  • Movement Disorders / diagnostic imaging*
  • Parkinson Disease / diagnostic imaging
  • Receptors, Dopamine / analysis*
  • Receptors, Dopamine / physiology
  • Receptors, GABA-A / analysis
  • Receptors, Opioid / analysis
  • Tomography, Emission-Computed*
  • Tourette Syndrome / diagnostic imaging

Substances

  • Receptors, Dopamine
  • Receptors, GABA-A
  • Receptors, Opioid
  • Levodopa
  • Dopamine