Human chromosome 10 loci map to three different sheep chromosomes

Mamm Genome. 1995 Jan;6(1):46-8. doi: 10.1007/BF00350893.

Abstract

The interleukin 2 receptor (IL2RA), a human Chromosome (Chr) 10p locus, was mapped to sheep Chr 13q12-q15 by in situ hybridization. Two loci from human Chr 10q, cytochrome P450 subfamily XVII (CYP17) and the tachykinin 2 receptor (TAC2R), were assigned to sheep Chrs 22q21-q23 and 25q14-q23 respectively. The assignment of IL2RA allows the provisional assignment of the previously unassigned sheep syntenic group U15 to sheep Chr 13. Sheep linkage group 5 is predicted to be located on sheep Chr 25 on the basis of the TAC2R assignment.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cattle / genetics
  • Chromosome Mapping / veterinary*
  • Chromosomes, Human, Pair 10*
  • Genetic Markers
  • Humans
  • In Situ Hybridization
  • Sheep / genetics*
  • Species Specificity

Substances

  • Genetic Markers