The nuclear pore complex and nucleocytoplasmic transport

Curr Opin Cell Biol. 1993 Jun;5(3):395-407. doi: 10.1016/0955-0674(93)90003-9.

Abstract

In the past year we have seen two new three-dimensional views of the nuclear pore complex, the discovery of a nuclear pore complex protein that contains zinc fingers, the purification of nuclear localization signal recognition proteins, and the discovery that hsc70 participates in nuclear import. Other highlights include the finding that certain proteins associated with heterogeneous nuclear RNA shuttle between the nucleus and cytoplasm, and that a nucleolar nuclear localization signal binding protein, which also shuttles, is located on intranuclear tracks.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Transport
  • Cell Nucleus / metabolism*
  • Cytoplasm / metabolism*
  • Humans
  • Membrane Glycoproteins / metabolism
  • Nuclear Envelope / metabolism*
  • Nuclear Pore Complex Proteins
  • Nuclear Proteins / metabolism
  • RNA / metabolism

Substances

  • Membrane Glycoproteins
  • Nuclear Pore Complex Proteins
  • Nuclear Proteins
  • nuclear pore protein p62
  • RNA