Abstract
Three-dimensional images of the open state of the nicotinic acetylcholine receptor have been obtained at 9 A resolution. Comparison with the closed state reveals the structural basis of channel gating.
MeSH terms
-
Acetylcholine / metabolism
-
Amino Acid Sequence
-
Ion Channel Gating / physiology*
-
Molecular Sequence Data
-
Protein Conformation
-
Receptors, Nicotinic / chemistry*
-
Receptors, Nicotinic / physiology*
Substances
-
Receptors, Nicotinic
-
Acetylcholine