Tourette Syndrome is a movement disorder of childhood onset, characterized by multiple motor and phonic tics. In addition to tics, some children exhibit repetitive habits and recurring thoughts, and others may manifest problems of inattention, impulsiveness, and hyperactivity. Over the past two decades there has been increased interest in Tourette Syndrome, because it provides a useful model for examining the interaction of genes and environment, as well as neurobiology and behavior. This article provides school nurses and nurses working in school-based clinics with a general review of Tourette Syndrome and associated disorders.