Menstrual cycle-related sensitivity to 35% CO2 in panic patients

Biol Psychiatry. 1995 Apr 15;37(8):528-32. doi: 10.1016/0006-3223(94)00154-U.

Abstract

In a double blind, random, cross-over design, 10 patients and seven controls inhaled one vital capacity of 35% CO2-65% O2 during their early-follicular and midluteal phases. Anxiety after CO2 intake was significantly stronger in the early-follicular phase than in the midluteal phase for patients. Controls had no anxiety reactions.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Administration, Inhalation
  • Adult
  • Anxiety / diagnosis
  • Anxiety / physiopathology
  • Arousal / physiology*
  • Carbon Dioxide*
  • Cross-Over Studies
  • Double-Blind Method
  • Female
  • Humans
  • Menstrual Cycle / physiology*
  • Panic Disorder / diagnosis
  • Panic Disorder / physiopathology*

Substances

  • Carbon Dioxide