Oral cryptococcosis in a patient with AIDS. A case report

Oral Dis. 1995 Jun;1(2):77-9. doi: 10.1111/j.1601-0825.1995.tb00163.x.

Abstract

A 59-year-old Caucasian male patient with AIDS is described who presented with an oral lesion of cryptococcosis. The gingival ulceration was the only detectable lesion of cryptococcosis. Diagnosis was established by histopathologic findings from biopsy and detection of serum cryptococcal antigen. The patient was treated with amphotericin B and flucytosine. After four weeks of therapy cryptococcal antigen turned negative. The oral ulceration diminished in size, but an inflammatory tissue reaction persisted.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections / drug therapy
  • AIDS-Related Opportunistic Infections / microbiology*
  • Amphotericin B / therapeutic use
  • Cryptococcosis / drug therapy
  • Cryptococcosis / etiology*
  • Dental Care for Chronically Ill
  • Drug Therapy, Combination
  • Fatal Outcome
  • Flucytosine / therapeutic use
  • Gingival Diseases / microbiology
  • Humans
  • Male
  • Middle Aged
  • Mouth Diseases / drug therapy
  • Mouth Diseases / etiology*
  • Mouth Diseases / microbiology
  • Ulcer / microbiology

Substances

  • Amphotericin B
  • Flucytosine