Non stochastic distribution of single channels in planar lipid bilayers

Biochim Biophys Acta. 1995 Feb 15;1233(2):105-10. doi: 10.1016/0005-2736(94)00231-d.

Abstract

The selectivity of the planar lipid bilayers modified by two channel-forming proteins (alpha-toxin S. aureus and colicin Ia) was examined. It was established that in all cases the value of zero current potential depended on the amount of open ion channels and increased with the number of channels (from one to about 5-7). These facts point out both the interactions among ion channels and their non stochastic distribution on the membrane surface.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Toxins / chemistry*
  • Colicins / chemistry*
  • Hemolysin Proteins / chemistry*
  • In Vitro Techniques
  • Ion Channel Gating
  • Ion Channels / chemistry*
  • Lipid Bilayers
  • Membrane Potentials
  • Stochastic Processes

Substances

  • Bacterial Toxins
  • Colicins
  • Hemolysin Proteins
  • Ion Channels
  • Lipid Bilayers
  • staphylococcal alpha-toxin