Co-morbidity in the older adult Parkinson's disease patient decreases functional status and quality of life, and increases the risk of permanent disability. Although many chronic conditions in the adult population can be prevented, or at least influenced by early detection and treatment many progressive neurologic disorders such as Parkinson's disease cannot. This pilot study describes the health maintenance and disease prevention behaviors of a group of patients with Parkinson's disease. Findings demonstrate that parkinsonians attend in a way similar to their peers without Parkinson's disease to most parameters of general health maintenance as established by the United States Preventive Task Force. In fact, in 11 out of 12 selective parameters, parkinsonians exhibit increased frequency of participation in the recommended behaviors. However, achievement of our national goals for health promotion and disease prevention will require additional efforts in this population. Emphasis should include the participation in Pap smears, mammograms, exercise, seat belt usage and adult immunizations, especially the pneumococcal vaccination. Neuroscience nurses can play an important role in reaching health promotion and disease prevention goals in persons with Parkinson's disease through patient education, advocacy, case management, anticipatory guidance and referrals to primary care providers.