Fifty smokers and fifty non-smokers were administered the MMPI's Manifest Anxiety Scale (MAS). Mean MAS scores for smokers were significantly higher than those of non-smokers. Item analysis revealed that smokers obtained higher scores than non-smokers on significantly more items in which anxiety is manifested by a physical symptom rather than a psychological symptom. It is possible that physical stimulation by nicotine may contribute to a more ready arousal to anxiety in smokers.