Mechanism of nifurtimox toxicity in different forms of Trypanosoma cruzi

Biochem Pharmacol. 1981 Jul 15;30(14):1947-51. doi: 10.1016/0006-2952(81)90204-5.
No abstract available

MeSH terms

  • Cells, Cultured
  • Hydrogen Peroxide / metabolism
  • NAD / metabolism
  • NADP / metabolism
  • Nifurtimox / pharmacology*
  • Nitrofurans / pharmacology*
  • Oxygen Consumption / drug effects
  • Trypanosoma cruzi / drug effects*
  • Trypanosoma cruzi / metabolism

Substances

  • Nitrofurans
  • NAD
  • NADP
  • Hydrogen Peroxide
  • Nifurtimox