Histopathological evaluation of griseofulvin therapy in lichen planus. A double-blind controlled study

Dermatologica. 1980;161(1):22-7. doi: 10.1159/000250326.

Abstract

In a double-blind trial on 44 patients having lichen planus, 500 mg griseofulvin-FP daily for 8 weeks produced significantly better results compared to a placebo. The clinical improvement was accompanied by corresponding histological changes.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Clinical Trials as Topic
  • Double-Blind Method
  • Female
  • Griseofulvin / therapeutic use*
  • Humans
  • Lichen Planus / drug therapy*
  • Lichen Planus / pathology
  • Male
  • Middle Aged
  • Skin / pathology
  • Time Factors

Substances

  • Griseofulvin