Clinical and immunological associations in myasthenia gravis. 1: Autoantibodies

J Neurol Neurosurg Psychiatry. 1980 Nov;43(11):967-70. doi: 10.1136/jnnp.43.11.967.

Abstract

Associations between female sex, HLA B8, positive anti-thyroid microsomal antibody and, to a lesser extent, antinuclear antibody were seen in 34 patients with myasthenia gravis. This supports the concept that the disease is heterogeneous. Anti-DNA antibodies, which were present in 62% of the patients, did not show such associations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antibodies, Antinuclear / analysis
  • Antibody Formation
  • Autoantibodies / analysis*
  • DNA / immunology
  • Female
  • HLA Antigens / genetics
  • Humans
  • Male
  • Microsomes / immunology
  • Myasthenia Gravis / immunology*
  • Phenotype
  • Thyroid Gland / immunology

Substances

  • Antibodies, Antinuclear
  • Autoantibodies
  • HLA Antigens
  • DNA