Abstract
Metallothionein inhibited in a concentration-dependent fashion the reduction of nitroblue tetrazolium [NBT] mediated by xanthine oxidase and by NADH-phenazine methosulfate. This catalytic activity of metallothionein for dismutation of O2- is dependent on the copper content in metallothionein.
MeSH terms
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Animals
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Catalase / metabolism
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Copper / pharmacology
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Kinetics
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Liver / metabolism*
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Metallothionein / metabolism*
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Nitroblue Tetrazolium*
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Oxidation-Reduction
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Rats
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Superoxide Dismutase / metabolism
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Tetrazolium Salts*
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Xanthine Oxidase / metabolism
Substances
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Tetrazolium Salts
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Nitroblue Tetrazolium
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Copper
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Metallothionein
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Catalase
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Superoxide Dismutase
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Xanthine Oxidase