The use of tacrine for tardive dyskinesia

Am J Psychiatry. 1983 Dec;140(12):1629-31. doi: 10.1176/ajp.140.12.1629.

Abstract

The authors administered 45-90 mg/day of tacrine to eight patients with tardive dyskinesia. After 2 weeks of treatment, there was a mean reduction in tardive dyskinesia scores of 43%. No improvement occurred when a placebo was used instead of tacrine.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Administration, Oral
  • Adult
  • Aminoacridines / therapeutic use*
  • Dyskinesia, Drug-Induced / drug therapy*
  • Dyskinesia, Drug-Induced / psychology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Tacrine / administration & dosage
  • Tacrine / therapeutic use*

Substances

  • Aminoacridines
  • Tacrine