A case of benign osteoblastoma of the skull is reported. The clinical picture began when the patient was 15 years old, with exophthalmos and blindness in the right eye. After the enucleation of this eye, the only symptoms were repetitive convulsive seizures. Radiologic studies done when the patient was 76 years old, and a postmortem examination following her death at this age, revealed a voluminous osteoblastoma localized in the anterior cranial fossa and invading the structures below. The clinical characteristics of osteoblastomas of the skull are briefly reviewed.