[Thermochemotherapy for malignant melanoma--combination therapy of ACNU and hyperthermia in mice]

Gan To Kagaku Ryoho. 1983 Oct;10(10):2179-87.
[Article in Japanese]

Abstract

The effect of a combination therapy of hyperthermia (43 degrees C, 30 min) and ACNU (10 mg/kg) on B 16 melanoma and C 24 melanoma in vivo was studied. This combination therapy was effective in both melanoma. In C 24 melanoma, remarkably the tumor regression and the partial destruction of the histological structure, were observed.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Antineoplastic Agents / administration & dosage*
  • Hot Temperature / therapeutic use*
  • Humans
  • Male
  • Melanoma / pathology
  • Melanoma / therapy*
  • Mice
  • Mice, Inbred BALB C
  • Neoplasm Transplantation
  • Nimustine
  • Nitrosourea Compounds / administration & dosage*
  • Skin Neoplasms / pathology
  • Skin Neoplasms / therapy*

Substances

  • Antineoplastic Agents
  • Nitrosourea Compounds
  • Nimustine