The structural basis of PPHN

Clin Perinatol. 1984 Oct;11(3):525-49.

Abstract

Discussed in this article are the three main anatomic types of persistent pulmonary hypertension of the newborn; (1) maladaptation of the pulmonary vascular bed; (2) excessive muscularization of the pulmonary vascular bed; and (3) underdevelopment of the pulmonary vascular bed.

Publication types

  • Review

MeSH terms

  • Amniotic Fluid
  • Animals
  • Arteries / pathology
  • Diagnosis, Differential
  • Heart Defects, Congenital / diagnosis
  • Heart Defects, Congenital / pathology
  • Heart Septal Defects, Ventricular / diagnosis
  • Heart Septal Defects, Ventricular / pathology
  • Hernia, Diaphragmatic / diagnosis
  • Hernia, Diaphragmatic / pathology
  • Hernias, Diaphragmatic, Congenital
  • Humans
  • Hypertension, Pulmonary / pathology
  • Infant, Newborn
  • Kidney / abnormalities
  • Lung / abnormalities
  • Lung / blood supply
  • Lung / pathology
  • Meconium
  • Persistent Fetal Circulation Syndrome / diagnosis
  • Persistent Fetal Circulation Syndrome / pathology*
  • Persistent Fetal Circulation Syndrome / physiopathology
  • Pneumonia, Aspiration / diagnosis
  • Pneumonia, Aspiration / etiology
  • Pneumonia, Aspiration / pathology
  • Prognosis
  • Pulmonary Alveoli / blood supply
  • Pulmonary Alveoli / pathology
  • Pulmonary Circulation
  • Rabbits
  • Rats
  • Sheep
  • Vascular Resistance
  • Vasoconstriction