Abstract
DNA sequencing shows that the intragenic duplication within the human haptoglobin Hp2 allele was formed by a non-homologous, probably random, crossing-over within different introns of two Hp1 genes, probably in an Hp1F / Hp1S heterozygote.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Alleles*
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Amino Acid Sequence
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Base Sequence
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Crossing Over, Genetic
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DNA Restriction Enzymes
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Genes*
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Genotype
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Haptoglobins / genetics*
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Heterozygote
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Humans
Substances
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Haptoglobins
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DNA Restriction Enzymes