Two distinct alpha1-adrenergic receptor sites in rat liver: differential binding of (--)-[3H]dihydroergocryptine. Effects of guanine nucleotides and proteolysis; implications for a two-site model of alpha-receptor regulation

Biochem Pharmacol. 1981 Jun 15;30(12):1665-75. doi: 10.1016/0006-2952(81)90395-6.
No abstract available

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Binding Sites
  • Chymotrypsin / pharmacology
  • Dihydroergotoxine / metabolism
  • Female
  • Guanine Nucleotides / pharmacology
  • In Vitro Techniques
  • Liver / metabolism*
  • Models, Chemical
  • Norepinephrine / metabolism
  • Phenoxybenzamine / pharmacology
  • Prazosin / metabolism
  • Rats
  • Receptors, Adrenergic / metabolism*
  • Receptors, Adrenergic, alpha / drug effects
  • Receptors, Adrenergic, alpha / metabolism*

Substances

  • Guanine Nucleotides
  • Receptors, Adrenergic
  • Receptors, Adrenergic, alpha
  • Phenoxybenzamine
  • Dihydroergotoxine
  • Chymotrypsin
  • Norepinephrine
  • Prazosin