Isolation and nucleotide sequence of a cloned cardionatrin cDNA

Biochem Biophys Res Commun. 1984 Aug 16;122(3):1076-82. doi: 10.1016/0006-291x(84)91201-4.

Abstract

A cloned cDNA which codes for the C-terminal 62 residues of the precursor molecule for the atrial natriuretic factor, cardionatrin, has been isolated and sequenced. The nucleotide sequence confirms the amino acid sequence of cardionatrin 1-28 previously determined, and positions this peptide at the C-terminal end of the precursor just two residues away from the termination codon.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Atrial Natriuretic Factor
  • Base Sequence
  • Cloning, Molecular*
  • DNA / isolation & purification*
  • Heart Atria / metabolism
  • Heart Ventricles / metabolism
  • Male
  • Muscle Proteins / genetics*
  • Myocardium / metabolism
  • Nucleic Acid Hybridization
  • Rats
  • Rats, Inbred Strains

Substances

  • Muscle Proteins
  • Atrial Natriuretic Factor
  • DNA

Associated data

  • GENBANK/K02062
  • GENBANK/K02063