Abstract
A commercial alpha-amylase inhibitor with potent inhibitory activity in vitro was used in a randomized double-blind, cross-over clinical trial in six nonobese, healthy adult males. In these subjects, this inhibitor had no effect on the response of blood glucose, insulin, or breath hydrogen to a standardized starch meal. It is concluded that this formulation has no effect on starch digestion in humans.
Publication types
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Clinical Trial
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Randomized Controlled Trial
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amylases / antagonists & inhibitors*
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Blood Glucose / metabolism
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Dietary Carbohydrates / metabolism*
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Humans
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Hydrogen / metabolism
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Insulin / blood
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alpha-Amylases / antagonists & inhibitors*
Substances
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Blood Glucose
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Dietary Carbohydrates
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Insulin
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Hydrogen
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Amylases
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alpha-Amylases