3. Genetic variations that modify drug response. Variations in detoxication enzymes during mammalian development

Ann N Y Acad Sci. 1968 Jul 31;151(2):887-99. doi: 10.1111/j.1749-6632.1968.tb48274.x.
No abstract available

MeSH terms

  • Age Factors
  • Animals
  • Animals, Newborn
  • Bilirubin / antagonists & inhibitors
  • Bilirubin / metabolism
  • Breeding
  • Enzymes / metabolism
  • Female
  • Glucuronates / antagonists & inhibitors
  • Glucuronates / metabolism
  • Hexobarbital / blood
  • Hexobarbital / pharmacology
  • Injections, Intraperitoneal
  • Liver / drug effects
  • Liver / enzymology*
  • Liver / growth & development*
  • Magnesium / pharmacology
  • Male
  • Mice
  • Microsomes, Liver / enzymology
  • Microsomes, Liver / metabolism
  • Nitrophenols / metabolism
  • Rabbits
  • Sex Factors
  • Sleep / drug effects
  • Species Specificity
  • Sulfates / metabolism
  • Time Factors
  • Transferases / metabolism

Substances

  • Enzymes
  • Glucuronates
  • Nitrophenols
  • Sulfates
  • Hexobarbital
  • Transferases
  • Magnesium
  • Bilirubin